| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDH1B1 |
| Gene ID: | 219 |
| Uniprot ID: | AL1B1_HUMAN |
| Immunogen Region: | 278-517 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3). |
| Immunogen Sequence: | NLKRVTLELGGKSPSIVLAD ADMEHAVEQCHEALFFNMGQ CCCAGSRTFVEESIYNEFLE RTVEKAKQRKVGNPFELDTQ QGPQVDKEQFERVLGYIQLG QKEGAKLLCGGERFGERGFF IKPTVFGGVQDDMRIAKEEI FGPVQPLFKFKKIEEVVERA NNTRYGLAAAVFTRDLDKAM YFTQALQAGTVWVNTYNIVT CHTPFGGFKESGNGRELGED GLKAYTEVKTVTIKVPQKN |
| Tissue Specificity | Liver, testis and to a lesser extent in brain. |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
| Protein Name | Aldehyde Dehydrogenase X - MitochondrialAldehyde Dehydrogenase 5Aldehyde Dehydrogenase Family 1 Member B1 |
| Database Links | Reactome: R-HSA-71384Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase X - Mitochondrial antibodyAnti-Aldehyde Dehydrogenase 5 antibodyAnti-Aldehyde Dehydrogenase Family 1 Member B1 antibodyAnti-ALDH1B1 antibodyAnti-ALDH5 antibodyAnti-ALDHX antibody |
Information sourced from Uniprot.org