Anti-Albumin/HSA nanobody [SAA0807] (STJN000014)
General Information
| Short Description | Alpaca monoclonal nanobody anti-Albumin is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0807 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | ALB |
| Gene ID | 213 |
| Uniprot ID | ALBU_HUMAN |
Additional Info
| Post Translational Modifications | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylated by FAM20C in the extracellular medium. Acetylated on Lys-223 by acetylsalicylic acid. |
| Function | Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin. |
| Protein Name | Albumin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-159418Reactome: R-HSA-189451Reactome: R-HSA-189483Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-8964058Reactome: R-HSA-9707564Reactome: R-HSA-9749641Reactome: R-HSA-9757110Reactome: R-HSA-9793528 |
| Cellular Localisation | Secreted |
| Alternative Nanobody Names | Anti-Albumin nanobodyAnti-ALB nanobodyAnti-GIG20 nanobodyAnti-GIG42 nanobodyAnti-PRO0903 nanobodyAnti-PRO1708 nanobodyAnti-PRO2044 nanobodyAnti-PRO2619 nanobodyAnti-PRO2675 nanobodyAnti-UNQ696 nanobodyAnti-PRO1341 nanobody |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Anti-Albumin/HSA nanobody [SAA0807] (STJN000014)
This nanobody binds Human Serum Albumin (HSA), corresponding to UniProt entry P02768, and has confirmed reactivity in human samples only.
This nanobody has been validated for use in ELISA. No other applications are currently listed for this product.
This nanobody is supplied in a VHH format bearing an 8His-Cys tag, and it is unconjugated, allowing flexibility for downstream labeling or immobilization workflows.
This nanobody is purified by Nickel column affinity chromatography and is confirmed at greater than 95% purity as determined by SDS-PAGE.
This nanobody should be stored at 4°C for short-term use of 1 to 2 weeks, at -20°C for up to 12 months, or at -80°C for long-term storage. A manual defrost freezer should be used, and repeated freeze-thaw cycles should be avoided.
This nanobody is supplied at 1 mg/mL in 0.01M PBS at pH 7.4.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.