Anti-AKT1/2 antibody (381-480) [S3MR] (STJ11103503)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal AKT1/2 (381-480) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKT1AKT2 |
| Gene ID | 207208 |
| Uniprot ID | AKT1_HUMANAKT2_HUMAN |
| Immunogen Region | 381-480 |
| Immunogen Sequence | SGLLKKDPKQRLGGGSEDAK EIMQHRFFAGIVWQHVYEKK LSPPFKPQVTSETDTRYFDE EFTAQMITITPPDQDDSMEC VDSERRPHFPQFSYSASGTA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 381-480 of human AKT1/2 (P31749). |
Additional Info
| Tissue Specificity | P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.P31751 - Widely expressed. Expressed in myoblasts. |
| Alternative Antibody Names | Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 antibodyAnti-PKB antibodyAnti-RAC antibodyAnti-Rac-Beta Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-2 antibodyAnti-Protein Kinase B Beta antibodyAnti-Pkb Beta antibodyAnti-Rac Protein Kinase Beta antibodyAnti-Rac-Pk-Beta antibodyAnti-AKT2 antibody |
Information sourced from Uniprot.org