Anti-AKAP6 antibody (1-270) (STJ114664)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AKAP6 (1-270) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKAP6 |
| Gene ID | 9472 |
| Uniprot ID | AKAP6_HUMAN |
| Immunogen Region | 1-270 |
| Immunogen Sequence | MLTMSVTLSPLRSQDLDPMA TDASPMAINMTPTVEQGEGE EAMKDMDSDQQYEKPPPLHT GADWKIVLHLPEIETWLRMT SERVRDLTYSVQQDSDSKHV DVHLVQLKDICEDISDHVEQ IHALLETEFSLKLLSYSVNV IVDIHAVQLLWHQLRVSVLV LRERILQGLQDANGNYTRQT DILQAFSEETKEGRLDSLTE VDDSGQLTIKCSQNYLSLDC GITAFELSDYSPSEDLLSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human AKAP6 (NP_004265.3). |
Additional Info
| Tissue Specificity | Highly expressed in cardiac and skeletal muscle, followed by brain. |
| Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes. |
| Protein Name | A-Kinase Anchor Protein 6Akap-6A-Kinase Anchor Protein 100 KdaAkap 100Protein Kinase A-Anchoring Protein 6Prka6Makap |
| Database Links | |
| Cellular Localisation | Sarcoplasmic ReticulumNucleus MembraneIn Heart MuscleParticipation Of Multiple Targeting Signals Allow Correct Intracellular TargetingThese May Be Repeated Motifs Rich In Basic And Hydrophobic Amino AcidsPalmitoylated/Myristoylated Motifs Or Alternatively Splice Targeting Sequences |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 6 antibodyAnti-Akap-6 antibodyAnti-A-Kinase Anchor Protein 100 Kda antibodyAnti-Akap 100 antibodyAnti-Protein Kinase A-Anchoring Protein 6 antibodyAnti-Prka6 antibodyAnti-Makap antibodyAnti-AKAP6 antibodyAnti-AKAP100 antibodyAnti-KIAA0311 antibody |
Information sourced from Uniprot.org