| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-AIP1/MAGI2 (C-Term) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MAGI2 |
| Gene ID: |
9863 |
| Uniprot ID: |
MAGI2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_036433.2 |
| Immunogen Sequence: |
PSVLKPGASAASR |
| Function | Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis. |
| Protein Name | Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2Atrophin-1-Interacting Protein 1Aip-1Atrophin-1-Interacting Protein AMembrane-Associated Guanylate Kinase Inverted 2Magi-2 |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | CytoplasmLate EndosomeSynapseSynaptosomeCell MembranePeripheral Membrane ProteinCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumCentriolePhotoreceptor Inner SegmentPhotoreceptor Outer SegmentLocalized Diffusely In The Cytoplasm Before Nerve Growth Factor (Ngf) StimulationRecruited To Late Endosomes After Ngf StimulationMembrane-Associated In Synaptosomes |
| Alternative Antibody Names | Anti-Membrane-Associated Guanylate Kinase - Ww And Pdz Domain-Containing Protein 2 antibodyAnti-Atrophin-1-Interacting Protein 1 antibodyAnti-Aip-1 antibodyAnti-Atrophin-1-Interacting Protein A antibodyAnti-Membrane-Associated Guanylate Kinase Inverted 2 antibodyAnti-Magi-2 antibodyAnti-MAGI2 antibodyAnti-ACVRINP1 antibodyAnti-AIP1 antibodyAnti-KIAA0705 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
