| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AIMP2 |
| Gene ID: |
7965 |
| Uniprot ID: |
AIMP2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of JTV1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human JTV1 |
| Function | Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. |
| Protein Name | Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2Multisynthase Complex Auxiliary Component P38Protein Jtv-1 |
| Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716 |
| Cellular Localisation | CytoplasmCytosolNucleusFollowing Dna DamageDissociates From The Aminoacyl-Trna Synthase Complex And Translocates From The Cytoplasm To The Nucleus |
| Alternative Antibody Names | Anti-Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2 antibodyAnti-Multisynthase Complex Auxiliary Component P38 antibodyAnti-Protein Jtv-1 antibodyAnti-AIMP2 antibodyAnti-JTV1 antibodyAnti-PRO0992 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
