Anti-AIMP2 antibody [SAA1667] (STJA0020095)

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STJA0020095
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Short Description :Mouse monoclonal Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2 antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :SAA1667
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:AIMP2
Gene ID:7965
Uniprot ID:AIMP2_HUMAN
Function Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Protein Name Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2
Multisynthase Complex Auxiliary Component P38
Protein Jtv-1
Database Links Reactome: R-HSA-2408522
Reactome: R-HSA-379716
Reactome: R-HSA-9856649
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Following Dna Damage
Dissociates From The Aminoacyl-Trna Synthase Complex And Translocates From The Cytoplasm To The Nucleus
Alternative Antibody Names Anti-Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2 antibody
Anti-Multisynthase Complex Auxiliary Component P38 antibody
Anti-Protein Jtv-1 antibody
Anti-AIMP2 antibody
Anti-JTV1 antibody
Anti-PRO0992 antibody

Information sourced from Uniprot.org

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