Anti-AIF1/Iba1 antibody (Full-Length) (STJA0003858)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFull-length human AIF1 expressed in and purified from E. coli
General Information
| Short Description | Rabbit polyclonal anti-AIF1/Iba1 (Full-Length) for use in WB and ICC in Human, Mouse and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen affinity purified serum |
| Dilution Range | WB 1:1000ICC 1:500-1:5000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AIF1 |
| Gene ID | 199 |
| Uniprot ID | AIF1_HUMAN |
| Immunogen | Full-length human AIF1 expressed in and purified from E. coli |
| Immunogen Region | Full-Length |
Additional Info
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Protein Name | Allograft Inflammatory Factor 1Aif-1Ionized Calcium-Binding Adapter Molecule 1Protein G1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionRuffle MembranePeripheral Membrane ProteinCytoplasmic SidePhagocytic CupAssociated With The Actin Cytoskeleton At Membrane Ruffles And At Sites Of Phagocytosis |
| Alternative Antibody Names | Anti-Allograft Inflammatory Factor 1 antibodyAnti-Aif-1 antibodyAnti-Ionized Calcium-Binding Adapter Molecule 1 antibodyAnti-Protein G1 antibodyAnti-AIF1 antibodyAnti-G1 antibodyAnti-IBA1 antibody |
Information sourced from Uniprot.org