Anti-AHI1 antibody (STJA0007312)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human AHI1
General Information
| Short Description | Rabbit polyclonal anti-Jouberin for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AHI1 |
| Gene ID | 54806 |
| Uniprot ID | AHI1_HUMAN |
| Immunogen | Synthesized peptide derived from human AHI1 |
| Specificity | This antibody detects endogenous levels of AHI1 at Human, Rat |
Additional Info
| Function | Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. |
| Protein Name | JouberinAbelson Helper Integration Site 1 Protein HomologAhi-1 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyCell JunctionAdherens JunctionMicrotubule Organizing CenterCentrosomeCentrioleIn The Retinal Photoreceptor Cell LayerLocalizes At The Connecting Cilium |
| Alternative Antibody Names | Anti-Jouberin antibodyAnti-Abelson Helper Integration Site 1 Protein Homolog antibodyAnti-Ahi-1 antibodyAnti-AHI1 antibody |
Information sourced from Uniprot.org