Anti-AHCY antibody (253-432) (STJ27253)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AHCY (253-432) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AHCY |
| Gene ID | 191 |
| Uniprot ID | SAHH_HUMAN |
| Immunogen Region | 253-432 |
| Immunogen Sequence | AMEGYEVTTMDEACQEGNIF VTTTGCIDIILGRHFEQMKD DAIVCNIGHFDVEIDVKWLN ENAVEKVNIKPQVDRYRLKN GRRIILLAEGRLVNLGCAMG HPSFVMSNSFTNQVMAQIEL WTHPDKYPVGVHFLPKKLDE AVAEAHLGKLNVKLTKLTEK QAQYLGMSCDGPFKPDHYRY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 253-432 of human AHCY (NP_000678.1). |
Additional Info
| Function | Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine. Binds copper ions. |
| Protein Name | AdenosylhomocysteinaseAdohcyaseS-Adenosyl-L-Homocysteine Hydrolase |
| Database Links | Reactome: R-HSA-156581Reactome: R-HSA-1614635Reactome: R-HSA-2408508Reactome: R-HSA-5578997 |
| Cellular Localisation | CytoplasmMelanosomeNucleusEndoplasmic ReticulumIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Adenosylhomocysteinase antibodyAnti-Adohcyase antibodyAnti-S-Adenosyl-L-Homocysteine Hydrolase antibodyAnti-AHCY antibodyAnti-SAHH antibody |
Information sourced from Uniprot.org