Anti-AGR2 antibody (21-175) (STJ29144)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AGR2 (21-175) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AGR2 |
| Gene ID | 10551 |
| Uniprot ID | AGR2_HUMAN |
| Immunogen Region | 21-175 |
| Immunogen Sequence | RDTTVKPGAKKDTKDSRPKL PQTLSRGWGDQLIWTQTYEE ALYKSKTSNKPLMIIHHLDE CPHSQALKKVFAENKEIQKL AEQFVLLNLVYETTDKHLSP DGQYVPRIMFVDPSLTVRAD ITGRYSNRLYAYEPADTALL LDNMKKALKLLKTEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1). |
Additional Info
| Tissue Specificity | Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. |
| Function | Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion. |
| Protein Name | Anterior Gradient Protein 2 HomologAg-2Hag-2Hpc8Secreted Cement Gland Protein Xag-2 Homolog |
| Database Links | |
| Cellular Localisation | SecretedEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Anterior Gradient Protein 2 Homolog antibodyAnti-Ag-2 antibodyAnti-Hag-2 antibodyAnti-Hpc8 antibodyAnti-Secreted Cement Gland Protein Xag-2 Homolog antibodyAnti-AGR2 antibodyAnti-AG2 antibodyAnti-UNQ515 antibodyAnti-PRO1030 antibody |
Information sourced from Uniprot.org