| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AGPAT3 |
| Gene ID: | 56894 |
| Uniprot ID: | PLCC_HUMAN |
| Immunogen Region: | 145-310 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 145-310 of human AGPAT3 (NP_064517.1). |
| Immunogen Sequence: | KRKWEEDRDTVVEGLRRLSD YPEYMWFLLYCEGTRFTETK HRVSMEVAAAKGLPVLKYHL LPRTKGFTTAVKCLRGTVAA VYDVTLNFRGNKNPSLLGIL YGKKYEADMCVRRFPLEDIP LDEKEAAQWLHKLYQEKDAL QEIYNQKGMFPGEQFKPARR PWTLLN |
| Tissue Specificity | Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. |
| Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. Has a preference for arachidonoyl-CoA as a donor. Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol. |
| Protein Name | 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma 1-Acylglycerol-3-Phosphate O-Acyltransferase 3 1-Agp Acyltransferase 3 1-Agpat 3 Lysophosphatidic Acid Acyltransferase Gamma Lpaat-Gamma |
| Database Links | Reactome: R-HSA-1483166 Reactome: R-HSA-6811436 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Nucleus Envelope |
| Alternative Antibody Names | Anti-1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma antibody Anti-1-Acylglycerol-3-Phosphate O-Acyltransferase 3 antibody Anti-1-Agp Acyltransferase 3 antibody Anti-1-Agpat 3 antibody Anti-Lysophosphatidic Acid Acyltransferase Gamma antibody Anti-Lpaat-Gamma antibody Anti-AGPAT3 antibody Anti-LPAAT3 antibody Anti-UNQ759 antibody Anti-PRO1490 antibody |
Information sourced from Uniprot.org