| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AGPAT3 (145-310) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AGPAT3 |
| Gene ID: |
56894 |
| Uniprot ID: |
PLCC_HUMAN |
| Immunogen Region: |
145-310 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 145-310 of human AGPAT3 (NP_064517.1). |
| Immunogen Sequence: |
KRKWEEDRDTVVEGLRRLSD YPEYMWFLLYCEGTRFTETK HRVSMEVAAAKGLPVLKYHL LPRTKGFTTAVKCLRGTVAA VYDVTLNFRGNKNPSLLGIL YGKKYEADMCVRRFPLEDIP LDEKEAAQWLHKLYQEKDAL QEIYNQKGMFPGEQFKPARR PWTLLN |
| Tissue Specificity | Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. |
| Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. Has a preference for arachidonoyl-CoA as a donor. Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol. |
| Protein Name | 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma1-Acylglycerol-3-Phosphate O-Acyltransferase 31-Agp Acyltransferase 31-Agpat 3Lysophosphatidic Acid Acyltransferase GammaLpaat-Gamma |
| Database Links | Reactome: R-HSA-1483166Reactome: R-HSA-6811436 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinNucleus Envelope |
| Alternative Antibody Names | Anti-1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma antibodyAnti-1-Acylglycerol-3-Phosphate O-Acyltransferase 3 antibodyAnti-1-Agp Acyltransferase 3 antibodyAnti-1-Agpat 3 antibodyAnti-Lysophosphatidic Acid Acyltransferase Gamma antibodyAnti-Lpaat-Gamma antibodyAnti-AGPAT3 antibodyAnti-LPAAT3 antibodyAnti-UNQ759 antibodyAnti-PRO1490 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
