Anti-AGL antibody [R93-4S-9] (STJA0035562)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human AGL
General Information
| Short Description | Rabbit monoclonal anti-AGL for use in WB, IHC-P, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R93-4S-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200IF 1:50-1:200FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | AGL |
| Gene ID | 178 |
| Uniprot ID | GDE_HUMAN |
| Immunogen | A synthesized peptide derived from human AGL |
Additional Info
| Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1.whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
| Post Translational Modifications | The N-terminus is blocked. Ubiquitinated. |
| Function | Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. |
| Protein Name | Glycogen Debranching EnzymeGlycogen Debrancher Includes - 4-Alpha-GlucanotransferaseOligo-1 -4-1 -4-Glucantransferase - Amylo-Alpha-1 -6-GlucosidaseAmylo-1 -6-GlucosidaseDextrin 6-Alpha-D-Glucosidase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | CytoplasmUnder Glycogenolytic Conditions Localizes To The Nucleus |
| Alternative Antibody Names | Anti-Glycogen Debranching Enzyme antibodyAnti-Glycogen Debrancher Includes - 4-Alpha-Glucanotransferase antibodyAnti-Oligo-1 -4-1 -4-Glucantransferase - Amylo-Alpha-1 -6-Glucosidase antibodyAnti-Amylo-1 -6-Glucosidase antibodyAnti-Dextrin 6-Alpha-D-Glucosidase antibodyAnti-AGL antibodyAnti-GDE antibody |
Information sourced from Uniprot.org