| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Arf-GAP domain and FG repeat-containing protein 1 for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AGFG1 |
| Gene ID: | 3267 |
| Uniprot ID: | AGFG1_HUMAN |
| Specificity: | AGFG1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | O-glycosylated. |
| Function | Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. |
| Protein Name | Arf-Gap Domain And Fg Repeat-Containing Protein 1Hiv-1 Rev-Binding ProteinNucleoporin-Like Protein RipRev-Interacting ProteinRev/Rex Activation Domain-Binding Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | NucleusCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Arf-Gap Domain And Fg Repeat-Containing Protein 1 antibodyAnti-Hiv-1 Rev-Binding Protein antibodyAnti-Nucleoporin-Like Protein Rip antibodyAnti-Rev-Interacting Protein antibodyAnti-Rev/Rex Activation Domain-Binding Protein antibodyAnti-AGFG1 antibodyAnti-HRB antibodyAnti-RAB antibodyAnti-RIP antibody |
Information sourced from Uniprot.org
