Anti-AFP antibody (360-609) (STJ22541)

Name: Anti-AFP antibody (360-609) (STJ22541)
SKU: STJ22541
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⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ22541

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Short Description	Rabbit polyclonal AFP (360-609) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	AFP
Gene ID	174
Uniprot ID	FETA_HUMAN
Immunogen Region	360-609
Immunogen Sequence	RRHPQLAVSVILRVAKGYQE LLEKCFQTENPLECQDKGEE ELQKYIQESQALAKRSCGLF QKLGEYYLQNAFLVAYTKKA PQLTSSELMAITRKMAATAA TCCQLSEDKLLACGEGAADI IIGHLCIRHEMTPVNPGVGQ CCTSSYANRRPCFSSLVVDE TYVPPAFSDDKFIFHKDLCQ AQGVALQTMKQEFLINLVKQ KPQITEEQLEAVIADFSGLL EKCCQGQEQEVCFAEEGQK
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 360-609 of human Alpha-Fetoprotein (Alpha-Fetoprotein (AFP) ) (NP_001125.1).

Tissue Specificity	Plasma. Synthesized by the fetal liver and yolk sac.
Post Translational Modifications	Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated.
Function	Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Protein Name	Alpha-Fetoprotein Alpha-1-Fetoprotein Alpha-Fetoglobulin
Database Links	Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Alpha-Fetoprotein antibody Anti-Alpha-1-Fetoprotein antibody Anti-Alpha-Fetoglobulin antibody Anti-AFP antibody Anti-HPAFP antibody

Information sourced from Uniprot.org