Anti-AFP antibody (19-609) [S9MM] (STJ119899)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal AFP (19-609) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MM |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000IHC-P:1:200-1:800IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AFP |
| Gene ID | 174 |
| Uniprot ID | FETA_HUMAN |
| Immunogen Region | 19-609 |
| Immunogen Sequence | RTLHRNEYGIASILDSYQCT AEISLADLATIFFAQFVQEA TYKEVSKMVKDALTAIEKPT GDEQSSGCLENQLPAFLEEL CHEKEILEKYGHSDCCSQSE EGRHNCFLAHKKPTPASIPL FQVPEPVTSCEAYEEDRETF MNKFIYEIARRHPFLYAPTI LLWAARYDKIIPSCCKAENA VECFQTKAATVTKELRESSL LNQHACAVMKNFGTRTFQAI TVTKLSQKFTKVNFTEIQK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 19-609 of human Alpha-Fetoprotein (AFP). |
Additional Info
| Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
| Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
| Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Protein Name | Alpha-FetoproteinAlpha-1-FetoproteinAlpha-Fetoglobulin |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-Fetoprotein antibodyAnti-Alpha-1-Fetoprotein antibodyAnti-Alpha-Fetoglobulin antibodyAnti-AFP antibodyAnti-HPAFP antibody |
Information sourced from Uniprot.org