Host: |
Mouse |
Applications: |
WB/IHC/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-AFP (19-609) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S9MM |
Conjugation: |
Unconjugated |
Isotype: |
IgG1k |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
AFP |
Gene ID: |
174 |
Uniprot ID: |
FETA_HUMAN |
Immunogen Region: |
19-609 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-609 of human Alpha-Fetoprotein (AFP). |
Immunogen Sequence: |
RTLHRNEYGIASILDSYQCT AEISLADLATIFFAQFVQEA TYKEVSKMVKDALTAIEKPT GDEQSSGCLENQLPAFLEEL CHEKEILEKYGHSDCCSQSE EGRHNCFLAHKKPTPASIPL FQVPEPVTSCEAYEEDRETF MNKFIYEIARRHPFLYAPTI LLWAARYDKIIPSCCKAENA VECFQTKAATVTKELRESSL LNQHACAVMKNFGTRTFQAI TVTKLSQKFTKVNFTEIQK |
Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
Protein Name | Alpha-FetoproteinAlpha-1-FetoproteinAlpha-Fetoglobulin |
Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Alpha-Fetoprotein antibodyAnti-Alpha-1-Fetoprotein antibodyAnti-Alpha-Fetoglobulin antibodyAnti-AFP antibodyAnti-HPAFP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance