Anti-AEBP2 antibody (234-503) (STJ29537)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AEBP2 (234-503) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AEBP2 |
| Gene ID | 121536 |
| Uniprot ID | AEBP2_HUMAN |
| Immunogen Region | 234-503 |
| Immunogen Sequence | STISSGRSTPAMMNGQGSTT SSSKNIAYNCCWDQCQACFN SSPDLADHIRSIHVDGQRGG VFVCLWKGCKVYNTPSTSQS WLQRHMLTHSGDKPFKCVVG GCNASFASQGGLARHVPTHF SQQNSSKVSSQPKAKEESPS KAGMNKRRKLKNKRRRSLPR PHDFFDAQTLDAIRHRAICF NLSAHIESLGKGHSVVFHST VIAKRKEDSGKIKLLLHWMP EDILPDVWVNESERHQLKT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human AEBP2 (NP_694939.2). |
Additional Info
| Function | Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex. |
| Protein Name | Zinc Finger Protein Aebp2Adipocyte Enhancer-Binding Protein 2Ae-Binding Protein 2 |
| Database Links | Reactome: R-HSA-212300Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusLocalizes To Chromatin As Part Of The Prc2 Complex |
| Alternative Antibody Names | Anti-Zinc Finger Protein Aebp2 antibodyAnti-Adipocyte Enhancer-Binding Protein 2 antibodyAnti-Ae-Binding Protein 2 antibodyAnti-AEBP2 antibody |
Information sourced from Uniprot.org