Anti-AEBP1 antibody (780-810 aa) (STJ191759)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 780-810
General Information
| Short Description | Rabbit polyclonal anti-Adipocyte enhancer-binding protein 1 (780-810 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AEBP1 |
| Gene ID | 165 |
| Uniprot ID | AEBP1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein at the amino acid range 780-810 |
| Immunogen Region | 780-810 aa |
| Specificity | AEBP1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
| Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
| Database Links | |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Adipocyte Enhancer-Binding Protein 1 antibodyAnti-Ae-Binding Protein 1 antibodyAnti-Aortic Carboxypeptidase-Like Protein antibodyAnti-AEBP1 antibodyAnti-ACLP antibody |
Information sourced from Uniprot.org