| Short Description : | Rabbit monoclonal Adenylosuccinate Synthetase Isozyme 2 (1-180) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4127RM |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADSS2 |
| Gene ID: | 159 |
| Uniprot ID: | PURA2_HUMAN |
| Immunogen Region: | 1-180 |
| Immunogen Sequence: | MAFAETYPAASSLPNGDCGR PRARPGGNRVTVVLGAQWGD EGKGKVVDLLAQDADIVCRC QGGNNAGHTVVVDSVEYDFH LLPSGIINPNVTAFIGNGVV IHLPGLFEEAEKNVQKGKGL EGWEKRLIISDRAHIVFDFH QAADGIQEQQRQEQAGKNLG TTKKGIGPVYSSKAARSGLR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human AdSS 2 (P30520). |
| Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
| Protein Name | Adenylosuccinate Synthetase Isozyme 2Ampsase 2Adss 2Adenylosuccinate Synthetase - Acidic IsozymeAdenylosuccinate Synthetase - Liver IsozymeL-Type Adenylosuccinate SynthetaseImp--Aspartate Ligase 2 |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | CytoplasmMitochondrionPartially Associated With Particulate Fractions |
| Alternative Antibody Names | Anti-Adenylosuccinate Synthetase Isozyme 2 antibodyAnti-Ampsase 2 antibodyAnti-Adss 2 antibodyAnti-Adenylosuccinate Synthetase - Acidic Isozyme antibodyAnti-Adenylosuccinate Synthetase - Liver Isozyme antibodyAnti-L-Type Adenylosuccinate Synthetase antibodyAnti-Imp--Aspartate Ligase 2 antibodyAnti-ADSS2 antibodyAnti-ADSS antibody |
Information sourced from Uniprot.org
![Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/99826/385443/STJ24063_1__97324.1713154337.jpg?c=1 "Confocal immunofluorescence analysis of HeLa cells using [KO Validated] HNRNPA2B1 Rabbit polyclonal antibody (STJ24063) at dilution of 1:400. Blue: DAPI for nuclear staining.")
