• Western blot analysis of extracts of various cell lines, using AdSS 2 antibody (STJ11104127) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-ADSS2 antibody (1-180) [S4127RM] (STJ11104127)

SKU:
STJ11104127

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Adenylosuccinate Synthetase Isozyme 2 (1-180) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S4127RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADSS2
Gene ID: 159
Uniprot ID: PURA2_HUMAN
Immunogen Region: 1-180
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human AdSS 2 (P30520).
Immunogen Sequence: MAFAETYPAASSLPNGDCGR PRARPGGNRVTVVLGAQWGD EGKGKVVDLLAQDADIVCRC QGGNNAGHTVVVDSVEYDFH LLPSGIINPNVTAFIGNGVV IHLPGLFEEAEKNVQKGKGL EGWEKRLIISDRAHIVFDFH QAADGIQEQQRQEQAGKNLG TTKKGIGPVYSSKAARSGLR
Function Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Protein Name Adenylosuccinate Synthetase Isozyme 2
Ampsase 2
Adss 2
Adenylosuccinate Synthetase - Acidic Isozyme
Adenylosuccinate Synthetase - Liver Isozyme
L-Type Adenylosuccinate Synthetase
Imp--Aspartate Ligase 2
Database Links Reactome: R-HSA-73817
Cellular Localisation Cytoplasm
Mitochondrion
Partially Associated With Particulate Fractions
Alternative Antibody Names Anti-Adenylosuccinate Synthetase Isozyme 2 antibody
Anti-Ampsase 2 antibody
Anti-Adss 2 antibody
Anti-Adenylosuccinate Synthetase - Acidic Isozyme antibody
Anti-Adenylosuccinate Synthetase - Liver Isozyme antibody
Anti-L-Type Adenylosuccinate Synthetase antibody
Anti-Imp--Aspartate Ligase 2 antibody
Anti-ADSS2 antibody
Anti-ADSS antibody

Information sourced from Uniprot.org

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