| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADSS2 |
| Gene ID: | 159 |
| Uniprot ID: | PURA2_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ADSS (NP_001117.2). |
| Immunogen Sequence: | MAFAETYPAASSLPNGDCGR PRARPGGNRVTVVLGAQWGD EGKGKVVDLLAQDADIVCRC QGGNNAGHTVVVDSVEYDFH LLPSGIINPNVTAFIGNGVV IHLPGLFEEAEKNVQKGKGL EGWEKRLIISDRAHIVFDFH QAADGIQEQQRQEQAGKNLG TTKKGIGPVYSSKAARSGLR MCDLVSDFDGFSERFKVLAN QYKSIYPTLEIDIEGELQKL KGYMEKIKPMVRDGVYFLY |
| Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
| Protein Name | Adenylosuccinate Synthetase Isozyme 2Ampsase 2Adss 2Adenylosuccinate Synthetase - Acidic IsozymeAdenylosuccinate Synthetase - Liver IsozymeL-Type Adenylosuccinate SynthetaseImp--Aspartate Ligase 2 |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | CytoplasmMitochondrionPartially Associated With Particulate Fractions |
| Alternative Antibody Names | Anti-Adenylosuccinate Synthetase Isozyme 2 antibodyAnti-Ampsase 2 antibodyAnti-Adss 2 antibodyAnti-Adenylosuccinate Synthetase - Acidic Isozyme antibodyAnti-Adenylosuccinate Synthetase - Liver Isozyme antibodyAnti-L-Type Adenylosuccinate Synthetase antibodyAnti-Imp--Aspartate Ligase 2 antibodyAnti-ADSS2 antibodyAnti-ADSS antibody |
Information sourced from Uniprot.org
