| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Beta-1 adrenergic receptor (281-330 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADRB1 |
| Gene ID: |
153 |
| Uniprot ID: |
ADRB1_HUMAN |
| Immunogen Region: |
281-330 aa |
| Specificity: |
AR-Beta 1 Polyclonal Antibody detects endogenous levels of AR-Beta 1 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ADRB1 at the amino acid range 281-330 |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneLocalized At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
| Alternative Antibody Names | Anti-Beta-1 Adrenergic Receptor antibodyAnti-Beta-1 Adrenoreceptor antibodyAnti-Beta-1 Adrenoceptor antibodyAnti-ADRB1 antibodyAnti-ADRB1R antibodyAnti-B1AR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
