| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADRA2B (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADRA2B |
| Gene ID: |
151 |
| Uniprot ID: |
ADA2B_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ADRA2B (NP_000673.2). |
| Immunogen Sequence: |
MDHQDPYSVQATAAIAAAIT FLILFTIFGNALVILAVLTS RSLRAPQNLFLVSLAAADIL VATLIIPFSLANELLGYWYF RRTWCEVYLALDVLFCTSSI |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. |
| Protein Name | Alpha-2b Adrenergic ReceptorAlpha-2 Adrenergic Receptor Subtype C2Alpha-2b AdrenoreceptorAlpha-2b AdrenoceptorAlpha-2bar |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-392023Reactome: R-HSA-418594Reactome: R-HSA-418597 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInteraction With Rab26Gga1Gga2 And Gga3 Mediates Transport From The Golgi To The Cell Membrane |
| Alternative Antibody Names | Anti-Alpha-2b Adrenergic Receptor antibodyAnti-Alpha-2 Adrenergic Receptor Subtype C2 antibodyAnti-Alpha-2b Adrenoreceptor antibodyAnti-Alpha-2b Adrenoceptor antibodyAnti-Alpha-2bar antibodyAnti-ADRA2B antibodyAnti-ADRA2L1 antibodyAnti-ADRA2RL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
