Anti-ADPRM antibody (203-342) (STJ114749)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADPRM (203-342) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADPRM |
| Gene ID | 56985 |
| Uniprot ID | ADPRM_HUMAN |
| Immunogen Region | 203-342 |
| Immunogen Sequence | SEPQFVQFNGGFSQEQLNWL NEVLTFSDTNQEKVVIVSHL PIYPDASDNVCLAWNYRDAL AVIWSHECVVCFFAGHTHDG GYSEDPFGVYHVNLEGVIET APDSQAFGTVHVYPDKMMLK GRGRVPDRIMNYKKERAFHC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3). |
Additional Info
| Function | Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress. |
| Protein Name | Manganese-Dependent Adp-Ribose/Cdp-Alcohol Diphosphatase Adpribase-MnCdp-Choline Phosphohydrolase |
| Database Links | Reactome: R-HSA-2393930 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Manganese-Dependent Adp-Ribose/Cdp-Alcohol Diphosphatase antibodyAnti-Adpribase-Mn antibodyAnti-Cdp-Choline Phosphohydrolase antibodyAnti-ADPRM antibodyAnti-C17orf48 antibodyAnti-MDS006 antibodyAnti-Nbla03831 antibody |
Information sourced from Uniprot.org