| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADPRM |
| Gene ID: | 56985 |
| Uniprot ID: | ADPRM_HUMAN |
| Immunogen Region: | 203-342 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3). |
| Immunogen Sequence: | SEPQFVQFNGGFSQEQLNWL NEVLTFSDTNQEKVVIVSHL PIYPDASDNVCLAWNYRDAL AVIWSHECVVCFFAGHTHDG GYSEDPFGVYHVNLEGVIET APDSQAFGTVHVYPDKMMLK GRGRVPDRIMNYKKERAFHC |
| Function | Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress. |
| Protein Name | Manganese-Dependent Adp-Ribose/Cdp-Alcohol Diphosphatase Adpribase-MnCdp-Choline Phosphohydrolase |
| Database Links | Reactome: R-HSA-2393930 |
| Alternative Antibody Names | Anti-Manganese-Dependent Adp-Ribose/Cdp-Alcohol Diphosphatase antibodyAnti-Adpribase-Mn antibodyAnti-Cdp-Choline Phosphohydrolase antibodyAnti-ADPRM antibodyAnti-C17orf48 antibodyAnti-MDS006 antibodyAnti-Nbla03831 antibody |
Information sourced from Uniprot.org