Anti-ADORA2A antibody (300-400) (STJ22527)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADORA2A (300-400) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADORA2A |
| Gene ID | 135 |
| Uniprot ID | AA2AR_HUMAN |
| Immunogen Region | 300-400 |
| Immunogen Sequence | RKIIRSHVLRQQEPFKAAGT SARVLAAHGSDGEQVSLRLN GHPPGVWANGSAPHPERRPN GYALGLVSGGSAQESQGNTG LPDVELLSHELKGVCPEPPG L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ADORA2A (NP_000666.2). |
Additional Info
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP4.leading to stabilization and expression at the cell surface. |
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Adenosine Receptor A2a |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-417973Reactome: R-HSA-418555Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gas2l2 At Neuronal Processes |
| Alternative Antibody Names | Anti-Adenosine Receptor A2a antibodyAnti-ADORA2A antibodyAnti-ADORA2 antibody |
Information sourced from Uniprot.org