Anti-ADO antibody (STJA0004706)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human ADO
General Information
| Short Description | Rabbit polyclonal anti-2-Aminoethanethiol Dioxygenase for use in WB, IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:1000-1:5000, IHC 1:25-1:100 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ADO |
| Gene ID | 84890 |
| Uniprot ID | AEDO_HUMAN |
| Immunogen | Synthetic peptide of human ADO |
Additional Info
| Function | Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate. Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine. Catalyzes the oxidation of regulators of G-protein signaling 4 (RGS4) and 5 (RGS5) and interleukin-32 (IL32). |
| Protein Name | 2-Aminoethanethiol DioxygenaseCysteamine Dioxygenase |
| Database Links | Reactome: R-HSA-1614558 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-2-Aminoethanethiol Dioxygenase antibodyAnti-Cysteamine Dioxygenase antibodyAnti-ADO antibodyAnti-C10orf22 antibody |
Information sourced from Uniprot.org