Anti-ADIRF antibody (25-75 aa) (STJ196226)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human APM2 at the amino acid range 25-75
General Information
| Short Description | Rabbit polyclonal anti-Adipogenesis regulatory factor (25-75 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADIRF |
| Gene ID | 10974 |
| Uniprot ID | ADIRF_HUMAN |
| Immunogen | Synthesized peptide derived from the human APM2 at the amino acid range 25-75 |
| Immunogen Region | 25-75 aa |
| Specificity | This antibody detects endogenous levels of APM2 at Human |
Additional Info
| Function | Plays a role in fat cell development.promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. |
| Protein Name | Adipogenesis Regulatory FactorAdipogenesis Factor Rich In ObesityAdipose Most Abundant Gene Transcript 2 ProteinAdipose-Specific Protein 2Apm-2 |
| Database Links | Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Adipogenesis Regulatory Factor antibodyAnti-Adipogenesis Factor Rich In Obesity antibodyAnti-Adipose Most Abundant Gene Transcript 2 Protein antibodyAnti-Adipose-Specific Protein 2 antibodyAnti-Apm-2 antibodyAnti-ADIRF antibodyAnti-AFRO antibodyAnti-APM2 antibodyAnti-C10orf116 antibody |
Information sourced from Uniprot.org