| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADIPOR2 (1-147) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADIPOR2 |
| Gene ID: |
79602 |
| Uniprot ID: |
PAQR2_HUMAN |
| Immunogen Region: |
1-147 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human ADIPOR2 (NP_078827.2). |
| Immunogen Sequence: |
MNEPTENRLGCSRTPEPDIR LRKGHQLDGTRRGDNDSHQG DLEPILEASVLSSHHKKSSE EHEYSDEAPQEDEGFMGMSP LLQAHHAMEKMEEFVCKVWE GRWRVIPHDVLPDWLKDNDF LLHGHRPPMPSFRACFKSIF RIHTETG |
| Tissue Specificity | Ubiquitous. Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. |
| Protein Name | Adiponectin Receptor Protein 2Progestin And Adipoq Receptor Family Member 2Progestin And Adipoq Receptor Family Member Ii |
| Database Links | Reactome: R-HSA-163680 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles |
| Alternative Antibody Names | Anti-Adiponectin Receptor Protein 2 antibodyAnti-Progestin And Adipoq Receptor Family Member 2 antibodyAnti-Progestin And Adipoq Receptor Family Member Ii antibodyAnti-ADIPOR2 antibodyAnti-PAQR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
