• Western blot analysis of extracts of various cell lines, using ADIPOR1 antibody (STJ118954) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-ADIPOR1 antibody (1-136) (STJ118954)

SKU:
STJ118954

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adiponectin Receptor 1 (1-136) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADIPOR1
Gene ID: 51094
Uniprot ID: PAQR1_HUMAN
Immunogen Region: 1-136
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human Adiponectin Receptor 1 (NP_057083.2).
Immunogen Sequence: MSSHKGSVVAQGNGAPASNR EADTVELAELGPLLEEKGKR VIANPPKAEEEQTCPVPQEE EEEVRVLTLPLQAHHAMEKM EEFVYKVWEGRWRVIPYDVL PDWLKDNDYLLHGHRPPMPS FRACFKSIFRIHTETG
Tissue Specificity Widely expressed. Highly expressed in heart and skeletal muscle. Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
Function Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin.
Protein Name Adiponectin Receptor Protein 1
Progestin And Adipoq Receptor Family Member 1
Progestin And Adipoq Receptor Family Member I
Database Links Reactome: R-HSA-163680
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized To The Cell Membrane And Intracellular Organelles
Alternative Antibody Names Anti-Adiponectin Receptor Protein 1 antibody
Anti-Progestin And Adipoq Receptor Family Member 1 antibody
Anti-Progestin And Adipoq Receptor Family Member I antibody
Anti-ADIPOR1 antibody
Anti-PAQR1 antibody
Anti-TESBP1A antibody
Anti-CGI-45 antibody

Information sourced from Uniprot.org

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