Anti-Adiponectin Receptor 2 antibody (78-219 aa) (STJA0040887)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeMixed
ImmunogenHuman Adiponectin Receptor 2 protein (amino acids: 78-219) conjugated to GST.
General Information
| Short Description | Rabbit polyclonal anti-Adiponectin Receptor 2 (78-219 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | Mixed |
| Conjugation | Unconjugated |
| Purification | Whole serum |
| Dilution Range | WB 1.4305555555555556 |
| Formulation | 15% glycerol |
| Storage Instruction | Aliquot and store at-20ยฐC for a higher stability. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ADIPOR2 |
| Gene ID | 79602 |
| Uniprot ID | PAQR2_HUMAN |
| Immunogen | Human Adiponectin Receptor 2 protein (amino acids: 78-219) conjugated to GST. |
| Immunogen Region | 78-219 aa |
| Immunogen Sequence | Human |
| Specificity | This antiserum is known to recognize both mouse and human Adiponectin Receptor 2. |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. |
| Protein Name | Adiponectin Receptor Protein 2Progestin And Adipoq Receptor Family Member 2Progestin And Adipoq Receptor Family Member Ii |
| Database Links | Reactome: R-HSA-163680 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles |
| Alternative Antibody Names | Anti-Adiponectin Receptor Protein 2 antibodyAnti-Progestin And Adipoq Receptor Family Member 2 antibodyAnti-Progestin And Adipoq Receptor Family Member Ii antibodyAnti-ADIPOR2 antibodyAnti-PAQR2 antibody |
Information sourced from Uniprot.org