| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hydroxyacid-Oxoacid Transhydrogenase-Mitochondrial is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification: |
Affinity purification |
| Concentration: |
0.2 mg/mL |
| Dilution Range: |
IHC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Only expressed in adult liver. |
| Function | Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. |
| Protein Name | Hydroxyacid-Oxoacid Transhydrogenase - MitochondrialHotAlcohol Dehydrogenase Iron-Containing Protein 1Adhfe1Fe-Containing Alcohol Dehydrogenase |
| Database Links | Reactome: R-HSA-880009 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Hydroxyacid-Oxoacid Transhydrogenase - Mitochondrial antibodyAnti-Hot antibodyAnti-Alcohol Dehydrogenase Iron-Containing Protein 1 antibodyAnti-Adhfe1 antibodyAnti-Fe-Containing Alcohol Dehydrogenase antibodyAnti-ADHFE1 antibodyAnti-HMFT2263 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
