Anti-ADH7 antibody (211-260 aa) (STJ91499)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ADH7 at the amino acid range 211-260
General Information
| Short Description | Rabbit polyclonal anti-All-trans-retinol dehydrogenase ADH7 (211-260 aa) for use in WB and ELISA in Human and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADH7 |
| Gene ID | 131 |
| Uniprot ID | ADH7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ADH7 at the amino acid range 211-260 |
| Immunogen Region | 211-260 aa |
| Specificity | ADH7 Polyclonal Antibody detects endogenous levels of ADH7 protein. |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh7Alcohol Dehydrogenase Class 4 Mu/Sigma ChainAlcohol Dehydrogenase Class Iv Mu/Sigma ChainGastric Alcohol DehydrogenaseOmega-Hydroxydecanoate Dehydrogenase Adh7Retinol Dehydrogenase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh7 antibodyAnti-Alcohol Dehydrogenase Class 4 Mu/Sigma Chain antibodyAnti-Alcohol Dehydrogenase Class Iv Mu/Sigma Chain antibodyAnti-Gastric Alcohol Dehydrogenase antibodyAnti-Omega-Hydroxydecanoate Dehydrogenase Adh7 antibodyAnti-Retinol Dehydrogenase antibodyAnti-ADH7 antibody |
Information sourced from Uniprot.org