Anti-ADGRG5 antibody (91-140 aa) (STJ93322)

SKU:
STJ93322
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Adhesion G-protein coupled receptor G5 (91-140 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ADGRG5
Gene ID:221188
Uniprot ID:AGRG5_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human GPR114 at the amino acid range 91-140
Immunogen Region:91-140 aa
Specificity:GPR114 Polyclonal Antibody detects endogenous levels of GPR114 protein.
Post Translational Modifications Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. N-glycsylated.
Function Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity.
Protein Name Adhesion G-Protein Coupled Receptor G5
G-Protein Coupled Receptor 114
G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal Fragment
Adgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal Fragment
Adgrg5 C-Terminal Fragment
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Adhesion G-Protein Coupled Receptor G5 antibody
Anti-G-Protein Coupled Receptor 114 antibody
Anti-G-Protein Coupled Receptor Pgr27 Cleaved Into - Adhesion G-Protein Coupled Receptor G5 - N-Terminal Fragment antibody
Anti-Adgrg5 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G5 - C-Terminal Fragment antibody
Anti-Adgrg5 C-Terminal Fragment antibody
Anti-ADGRG5 antibody
Anti-GPR114 antibody
Anti-PGR27 antibody
Anti-UNQ2524 antibody
Anti-PRO6017 antibody

Information sourced from Uniprot.org