• Western blot analysis of the lysates from HUVECcells using EMR2 antibody.
  • Immunofluorescence analysis of COS7 cells, using EMR2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COLO cells, using EMR2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of COLO cells using EMR2 Polyclonal Antibody

Anti-ADGRE2 antibody (765-814 aa) (STJ92911)

SKU:
STJ92911

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adhesion G protein-coupled receptor E2 (765-814 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADGRE2
Gene ID: 30817
Uniprot ID: AGRE2_HUMAN
Immunogen Region: 765-814 aa
Specificity: EMR2 Polyclonal Antibody detects endogenous levels of EMR2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human EMR2 at the amino acid range 765-814
Post Translational Modifications Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation.
Protein Name Adhesion G Protein-Coupled Receptor E2
Egf-Like Module Receptor 2
Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2
Cd Antigen Cd312
Database Links Reactome: R-HSA-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Ruffle Membrane
Localized At The Leading Edge Of Migrating Cells
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor E2 antibody
Anti-Egf-Like Module Receptor 2 antibody
Anti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2 antibody
Anti-Cd Antigen Cd312 antibody
Anti-ADGRE2 antibody
Anti-EMR2 antibody

Information sourced from Uniprot.org

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