Anti-ADGRE1 antibody (477-596) (STJ23535)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EMR1 (477-596) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADGRE1 |
| Gene ID | 2015 |
| Uniprot ID | AGRE1_HUMAN |
| Immunogen Region | 477-596 |
| Immunogen Sequence | GVAFVSFVGMESVLNERFFK DHQAPLTTSEIKLKMNSRVV GGIMTGEKKDGFSDPIIYTL ENIQPKQKFERPICVSWSTD VKGGRWTSFGCVILEASETY TICSCNQMANLAVIMASGEL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 477-596 of human EMR1 (NP_001965.3). |
Additional Info
| Tissue Specificity | Expression is restricted to eosinophils. |
| Function | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
| Protein Name | Adhesion G Protein-Coupled Receptor E1Egf-Like Module Receptor 1Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1Emr1 Hormone Receptor |
| Database Links | Reactome: R-HSA-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E1 antibodyAnti-Egf-Like Module Receptor 1 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibodyAnti-Emr1 Hormone Receptor antibodyAnti-ADGRE1 antibodyAnti-EMR1 antibodyAnti-TM7LN3 antibody |
Information sourced from Uniprot.org