Anti-ADGRB2 antibody (91-140 aa) (STJ91811)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human BAI2 at the amino acid range 91-140
General Information
| Short Description | Rabbit polyclonal anti-Adhesion G protein-coupled receptor B2 (91-140 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADGRB2 |
| Gene ID | 576 |
| Uniprot ID | AGRB2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human BAI2 at the amino acid range 91-140 |
| Immunogen Region | 91-140 aa |
| Specificity | BAI-2 Polyclonal Antibody detects endogenous levels of BAI-2 protein. |
Additional Info
| Post Translational Modifications | Glycosylated. Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment. |
| Function | Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition. |
| Protein Name | Adhesion G Protein-Coupled Receptor B2Brain-Specific Angiogenesis Inhibitor 2 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSecreted |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor B2 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 2 antibodyAnti-ADGRB2 antibodyAnti-BAI2 antibody |
Information sourced from Uniprot.org