Anti-Adenylate cyclase 1 antibody (C-Term) (STJ502053)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-Adenylate cyclase 1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | ELISA/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55-0.72 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500ELISA: 1:10, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Adcy1 |
| Gene ID | 432530 |
| Uniprot ID | ADCY1_MOUSE |
| Immunogen | Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein. |
| Immunogen Region | C-Term |
Additional Info
| Tissue Specificity | Expressed throughout inner ear development. |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. |
| Protein Name | Adenylate Cyclase Type 1Atp Pyrophosphate-Lyase 1Adenylate Cyclase Type IAdenylyl Cyclase 1Ca(2+/Calmodulin-Activated Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-163615Reactome: -MMU-170660Reactome: -MMU-170670Reactome: -MMU-418597Reactome: -MMU-5610787 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmMembrane RaftExpressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea VestibuleAs Well As To The Cochlear Hair Cell Nuclei And Stereocilia| |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 1 antibodyAnti-Atp Pyrophosphate-Lyase 1 antibodyAnti-Adenylate Cyclase Type I antibodyAnti-Adenylyl Cyclase 1 antibodyAnti-Ca(2+/Calmodulin-Activated Adenylyl Cyclase antibodyAnti-Adcy1 antibody |
Information sourced from Uniprot.org