Anti-ADCYAP1R1 antibody (80-160 aa) (STJ192784)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 80-160
General Information
| Short Description | Rabbit polyclonal anti-Pituitary adenylate cyclase-activating polypeptide type I receptor (80-160 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCYAP1R1 |
| Gene ID | 117 |
| Uniprot ID | PACR_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 80-160 |
| Immunogen Region | 80-160 aa |
| Specificity | PACR Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | G protein-coupled receptor activated by the neuropeptide pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds both PACAP27 and PACAP38 bioactive peptides. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
| Protein Name | Pituitary Adenylate Cyclase-Activating Polypeptide Type I ReceptorPac1 ReceptorPac1rPacap Type I ReceptorPacap-R-1Pacap-R1 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor antibodyAnti-Pac1 Receptor antibodyAnti-Pac1r antibodyAnti-Pacap Type I Receptor antibodyAnti-Pacap-R-1 antibodyAnti-Pacap-R1 antibodyAnti-ADCYAP1R1 antibody |
Information sourced from Uniprot.org