Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
Protein Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide antibodyAnti-Pacap Cleaved Into - Pacap-Related Peptide antibodyAnti-Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 antibodyAnti-Pacap-27 antibodyAnti-Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 antibodyAnti-Pacap-38 antibodyAnti-Pacap38 antibodyAnti-ADCYAP1 antibody |
Information sourced from Uniprot.org