Anti-ADCYAP1 antibody (125-176) {Biotin} (STJ502081)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-ADCYAP1 (125-176) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.5-1.5 ยตg/ยตl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:250 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCYAP1 |
| Gene ID | 116 |
| Uniprot ID | PACA_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein. |
| Immunogen Region | 125-176 |
Additional Info
| Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| Protein Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide antibodyAnti-Pacap Cleaved Into - Pacap-Related Peptide antibodyAnti-Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 antibodyAnti-Pacap-27 antibodyAnti-Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 antibodyAnti-Pacap-38 antibodyAnti-Pacap38 antibodyAnti-ADCYAP1 antibody |
Information sourced from Uniprot.org