| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADCYAP1 (125-176) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.5-1.5 µg/µl |
| Dilution Range: |
WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200IHC: 1:50-1:250 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ADCYAP1 |
| Gene ID: |
116 |
| Uniprot ID: |
PACA_HUMAN |
| Immunogen Region: |
125-176 |
| Immunogen: |
Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein. |
| Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| Protein Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide antibodyAnti-Pacap Cleaved Into - Pacap-Related Peptide antibodyAnti-Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 antibodyAnti-Pacap-27 antibodyAnti-Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 antibodyAnti-Pacap-38 antibodyAnti-Pacap38 antibodyAnti-ADCYAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
