Anti-ADCY10 antibody (368-418 aa) (STJ194997)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ADCYA at the amino acid range 368-418
General Information
| Short Description | Rabbit polyclonal anti-Adenylate cyclase type 10 (368-418 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCY10 |
| Gene ID | 55811 |
| Uniprot ID | ADCYA_HUMAN |
| Immunogen | Synthesized peptide derived from the human ADCYA at the amino acid range 368-418 |
| Immunogen Region | 368-418 aa |
| Specificity | This antibody detects endogenous levels of ADCYA at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Protein Name | Adenylate Cyclase Type 10Ah-Related ProteinAdenylate Cyclase HomologGerm Cell Soluble Adenylyl CyclaseHsacSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-HSA-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 10 antibodyAnti-Ah-Related Protein antibodyAnti-Adenylate Cyclase Homolog antibodyAnti-Germ Cell Soluble Adenylyl Cyclase antibodyAnti-Hsac antibodyAnti-Sac antibodyAnti-Testicular Soluble Adenylyl Cyclase antibodyAnti-ADCY10 antibodyAnti-SAC antibody |
Information sourced from Uniprot.org