| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ADAM19 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.1-0.3µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ADAM19 |
| Gene ID: |
8728 |
| Uniprot ID: |
ADA19_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_150377.1 |
| Immunogen Sequence: |
KIQCQSSEARPLESN |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 19Adam 19Meltrin-BetaMetalloprotease And Disintegrin Dendritic Antigen MarkerMaddam |
| Database Links | Reactome: R-HSA-8941237Reactome: R-HSA-9762292 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 19 antibodyAnti-Adam 19 antibodyAnti-Meltrin-Beta antibodyAnti-Metalloprotease And Disintegrin Dendritic Antigen Marker antibodyAnti-Maddam antibodyAnti-ADAM19 antibodyAnti-MLTNB antibodyAnti-FKSG34 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
