Anti-ACTL7A antibody (STJA0007386)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ACTL7A
General Information
| Short Description | Rabbit polyclonal anti-Actin-like protein 7A for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACTL7A |
| Gene ID | 10881 |
| Uniprot ID | ACL7A_HUMAN |
| Immunogen | Synthesized peptide derived from human ACTL7A |
| Specificity | This antibody detects endogenous levels of ACTL7A at Human, Mouse, Rat |
Additional Info
| Function | Essential for normal spermatogenesis and male fertility. Required for normal sperm head morphology, acroplaxome formation, acrosome attachment, and acrosome granule stability. May anchor and stabilize acrosomal adherence to the acroplaxome at least in part by facilitating the presence of F-actin in the subacrosomal space. May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis. |
| Protein Name | Actin-Like Protein 7aActin-Like-7-Alpha |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonGolgi ApparatusNucleusCytoplasmic VesicleSecretory VesicleAcrosomeDetected At The Golgi Apparatus During Acrosome BiogenesisDetected At The Subacrosomal Layer In Round SpermatidsDetected In Sperm Head And Tail |
| Alternative Antibody Names | Anti-Actin-Like Protein 7a antibodyAnti-Actin-Like-7-Alpha antibodyAnti-ACTL7A antibody |
Information sourced from Uniprot.org