| Short Description : | Rabbit polyclonal anti-Acetyl-coenzyme A synthetase 2-like, mitochondrial (620-689 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACSS1 |
| Gene ID: | 84532 |
| Uniprot ID: | ACS2L_HUMAN |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 620-689 |
| Immunogen Region: | 620-689 aa |
| Specificity: | The antibody detects endogenous ACSS1 protein |
| Function | Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. |
| Protein Name | Acetyl-Coenzyme A Synthetase 2-Like - MitochondrialAcetate--Coa Ligase 2Acetyl-Coa Synthetase 2Acecs2Acyl-Coa Synthetase Short-Chain Family Member 1Propionate--Coa Ligase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Acetyl-Coenzyme A Synthetase 2-Like - Mitochondrial antibodyAnti-Acetate--Coa Ligase 2 antibodyAnti-Acetyl-Coa Synthetase 2 antibodyAnti-Acecs2 antibodyAnti-Acyl-Coa Synthetase Short-Chain Family Member 1 antibodyAnti-Propionate--Coa Ligase antibodyAnti-ACSS1 antibodyAnti-ACAS2L antibodyAnti-KIAA1846 antibody |
Information sourced from Uniprot.org
