Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ACOT2 (222-483) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ACOT2 |
Gene ID: |
10965 |
Uniprot ID: |
ACOT2_HUMAN |
Immunogen Region: |
222-483 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 222-483 of human ACOT2 (NP_006812.3). |
Immunogen Sequence: |
IVDMFGTGGGLLEYRASLLA GKGFAVMALAYYNYEDLPKT METLHLEYFEEAMNYLLSHP EVKGPGVGLLGISKGGELCL SMASFLKGITAAVVINGSVA NVGGTLHYKGETLPPVGVNR NRIKVTKDGYADIVDVLNSP LEGPDQKSFIPVERAESTFL FLVGQDDHNWKSEFYANEAC KRLQAHGRRKPQIICYPETG HYIEPPYFPLCRASLHALVG SPIIWGGEPRAHAMAQVDA |
Tissue Specificity | Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas. |
Function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria. |
Protein Name | Acyl-Coenzyme A Thioesterase 2 - MitochondrialAcyl-Coa Thioesterase 2Acyl-Coenzyme A Thioester Hydrolase 2aCte-IaLong-Chain Acyl-Coa Thioesterase 2Zap128 |
Database Links | Reactome: R-HSA-77289Reactome: R-HSA-9033241 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-Acyl-Coenzyme A Thioesterase 2 - Mitochondrial antibodyAnti-Acyl-Coa Thioesterase 2 antibodyAnti-Acyl-Coenzyme A Thioester Hydrolase 2a antibodyAnti-Cte-Ia antibodyAnti-Long-Chain Acyl-Coa Thioesterase 2 antibodyAnti-Zap128 antibodyAnti-ACOT2 antibodyAnti-PTE2 antibodyAnti-PTE2A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance