| Host: | Mouse |
| Applications: | WB/ICC/FC |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-ATP-citrate synthase-lyase is suitable for use in Western Blot, Immunocytochemistry and Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 3D9-E9-H8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000ICC 1:150FCM 1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACLY |
| Gene ID: | 47 |
| Uniprot ID: | ACLY_HUMAN |
| Specificity: | This antibody detects endogenous levels of ATP-Citrate Lyase and does not cross-react with related proteins. |
| Immunogen: | Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli. |
| Function | Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis. |
| Protein Name | Atp-Citrate SynthaseAtp-CitratePro-S--LyaseAclCitrate Cleavage Enzyme |
| Database Links | Reactome: R-HSA-163765Reactome: R-HSA-6798695Reactome: R-HSA-75105 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Atp-Citrate Synthase antibodyAnti-Atp-Citrate antibodyAnti-Pro-S--Lyase antibodyAnti-Acl antibodyAnti-Citrate Cleavage Enzyme antibodyAnti-ACLY antibody |
Information sourced from Uniprot.org
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