| Short Description : | Mouse monoclonal anti-Acetyl-Histone H3.1-K9 for use in WB, IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF |
| Host: | Mouse |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 2E7 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:50-300WB 1:500-2000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | H3C1.H3C2.H3C3.H3C4.H3C6.H3C7.H3C8.H3C10.H3C11.H3C12 |
| Gene ID: | 8350/8351/8352/8353/8354/8355/8356/8357/8358/8968 |
| Uniprot ID: | H31_HUMAN |
| Immunogen: | Synthetic Peptide of Acetyl-Histone H3 (K9) |
| Specificity: | Acetyl-Histone H3 (K9) Monoclonal Antibody (2E7) detects endogenous levels of HIST1H3A |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.1Histone H3/AHistone H3/BHistone H3/CHistone H3/DHistone H3/FHistone H3/HHistone H3/IHistone H3/JHistone H3/KHistone H3/L |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-1912408Reactome: R-HSA-201722Reactome: R-HSA-212300Reactome: R-HSA-2299718Reactome: R-HSA-2559580Reactome: R-HSA-2559582Reactome: R-HSA-3214815Reactome: R-HSA-3214841Reactome: R-HSA-3214842Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-3247509Reactome: R-HSA-427359Reactome: R-HSA-427389Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-5334118Reactome: R-HSA-5578749Reactome: R-HSA-5617472Reactome: R-HSA-5625886Reactome: R-HSA-68616Reactome: R-HSA-73728Reactome: R-HSA-73772Reactome: R-HSA-8936459Reactome: R-HSA-8939236Reactome: R-HSA-9018519Reactome: R-HSA-912446Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9616222Reactome: R-HSA-9710421Reactome: R-HSA-977225Reactome: R-HSA-9821002Reactome: R-HSA-983231Reactome: R-HSA-9841922Reactome: R-HSA-9843940Reactome: R-HSA-9843970Reactome: R-HSA-9845323 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H3.1 antibodyAnti-Histone H3/A antibodyAnti-Histone H3/B antibodyAnti-Histone H3/C antibodyAnti-Histone H3/D antibodyAnti-Histone H3/F antibodyAnti-Histone H3/H antibodyAnti-Histone H3/I antibodyAnti-Histone H3/J antibodyAnti-Histone H3/K antibodyAnti-Histone H3/L antibodyAnti-H3C1 antibodyAnti-H3FA antibodyAnti-HIST1H3A.H3C2 antibodyAnti-H3FL antibodyAnti-HIST1H3B.H3C3 antibodyAnti-H3FC antibodyAnti-HIST1H3C.H3C4 antibodyAnti-H3FB antibodyAnti-HIST1H3D.H3C6 antibodyAnti-H3FD antibodyAnti-HIST1H3E.H3C7 antibodyAnti-H3FI antibodyAnti-HIST1H3F.H3C8 antibodyAnti-H3FH antibodyAnti-HIST1H3G.H3C10 antibodyAnti-H3FK antibodyAnti-HIST1H3H.H3C11 antibodyAnti-H3FF antibodyAnti-HIST1H3I.H3C12 antibodyAnti-H3FJ antibodyAnti-HIST1H3J antibody |
Information sourced from Uniprot.org
